Autism spectrum disorders may be associated with an increased risk of developing cardiometabolic disease, according to a review published online Jan. 30. JAMA Pediatrics.
Chathurika S. Dhanasekara, MD, Ph.D., Texas Tech University Health Sciences Center, Lubbock, and colleagues conducted a systematic literature review to examine the association between autism spectrum disorders and cardiometabolic disorders. bottom.
Based on 34 studies (276,173 autistic participants and 7.7 million non-autistic participants), autism was associated with overall diabetes (relative risk 1.57; 20 studies), (relative risk 1.64; 6 studies), the researchers found. ), and type 2 diabetes (relative risk, 2.47; 3 studies). An association was also observed between autism and an increased risk of dyslipidemia (relative risk 1.69; 7 studies) and heart disease (relative risk 1.46; 3 studies). No significant association was found between autism and risk of hypertension or stroke.
“The results should encourage clinicians to closely monitor potential causes, cardiometabolic disease manifestations, and their complications in people with autism due to the associated increased risk of cardiometabolic disease.” suggests that,” the authors wrote.
For more information:
Chathurika S. Dhanasekara et al., Association of Autism Spectrum Disorders with Cardiometabolic Diseases. JAMA Pediatrics (2023). DOI: 10.1001/jamapediatrics.2022.5629
Elizabeth M. Weir, Autism, Physical Health Conditions, and the Need for Reform, JAMA Pediatrics (2023). DOI: 10.1001/jamapediatrics.2022.5639
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