Ada Website Helper

    Subscribe to Updates

    Get the latest creative news from FooBar about art, design and business.

    What's Hot

    Philly Mayor Richardson Dilworth Redevelopment Begins

    January 27, 2023

    Brandt introduces bill to ban organ donation discrimination based on disability

    January 27, 2023

    Fusion of art, culture and literature

    January 27, 2023
    Facebook Twitter Instagram
    Ada Website Helper
    • Home
    • Autism

      Jason Kelce and his wife, Kylie, are the driving force behind the Eagles Autism Foundation

      January 27, 2023

      Steinhardt introduces bill to make traffic stops safer for autistic drivers

      January 27, 2023

      NIH Program Study Links Prenatal Perfluorononanoic Acid Exposure to Pediatric Autism-Related Features

      January 27, 2023

      NIH Program Study Links Prenatal Perfluorononanoic Acid Exposure to Pediatric Autism-Related Features

      January 27, 2023

      ADHD strongly linked to anxiety, depression and autism: study

      January 27, 2023
    • Disabilities

      Brandt introduces bill to ban organ donation discrimination based on disability

      January 27, 2023

      Learning disabilities – The Economic Times

      January 27, 2023

      Disabled couple happy with accessible OKC Habitat Home

      January 27, 2023

      Caregiver crisis hits LGBTQ older and disabled hardest

      January 27, 2023

      Q&A: A deaf Saskatoon writer finds art in his disability

      January 27, 2023
    • Disability

      Retirement and Disability Research Consortium Cooperation Agreement – ​​InsuranceNewsNet

      January 27, 2023

      How executives overcame obstacles and developed a sense of belonging

      January 27, 2023

      Here are the number of people living with a disability in Oxford

      January 27, 2023

      NIH is being asked to change its ‘Competent’ mission statement

      January 27, 2023

      Families of Oregon students with disabilities search for solutions in face of insufficient academic support

      January 27, 2023
    • Literature

      Fusion of art, culture and literature

      January 27, 2023

      Exhibition: A major attraction for art and literary works at the Patiala Heritage Festival

      January 27, 2023

      TETE ATETE Latest Education News with Renowned Translators of Hindi and Urdu Literature | Global Education News

      January 27, 2023

      Didion Dunn archives acquired by the New York Public Library

      January 27, 2023

      Tete Atete with renowned translators of Hindi and Urdu literature – The Times of Bengal

      January 27, 2023
    • Living

      News and analysis for those planning or nearing retirement

      January 27, 2023

      Living with the Good and Evil of Jordan Poole

      January 27, 2023

      All Saints Abbey of Etna transformed into apartment life

      January 27, 2023

      Half Moon Bay shooting: Supervisor tours ‘dire’ living conditions at mushroom farm where farm worker was killed

      January 27, 2023

      What I learned from living with ALS | 5 things I learned from nursing care that I want to tell my pre-ALS self

      January 27, 2023
    • Society

      Philly Mayor Richardson Dilworth Redevelopment Begins

      January 27, 2023

      Las Vegas Ace Star Chelsea Gray Joins Gaming Society Board of Directors

      January 27, 2023

      Purdue Northwest’s Leadership Institute and Society of Innovators Release 2023 Women on the Rise List and Reception – NWILife

      January 27, 2023

      Baird Named President and CEO of NC Aquarium Association

      January 27, 2023

      ICTC Student Joins Honors | School

      January 27, 2023
    Facebook Twitter Instagram
    Ada Website Helper
    Home»Autism»Autism risk associated with when and where ancestry lived
    Autism

    Autism risk associated with when and where ancestry lived

    adawebsitehelper_ts8fwmBy adawebsitehelper_ts8fwmJanuary 12, 20235 Mins Read
    Facebook Twitter Pinterest LinkedIn WhatsApp Reddit Tumblr Email
    Share
    Facebook Twitter LinkedIn Pinterest Email


    Autism risk associated with when and where ancestry lived

    Cluster of residences of paternal grandparents of ASD cases in Utah. credit: International Journal of Health Geographics (2022). DOI: 10.1186/s12942-022-00313-4

    When and where are often key clues for epidemiologists, medical sleuths who help solve the underlying mysteries of disease. The technology dates back at least to his 19th-century London, where a doctor named John Snow mapped cholera deaths and traced the origin of the outbreak to his one well in the city. The epidemic ended when the well was closed.

    Taking this idea to a new level, health scientists at the University of Utah, using a unique combination of geographic and demographic data, recently discovered when and where the parents and grandparents of children in Utah were born and raised with autism. concluded that it may contribute to an increased risk of descendants.

    Scientists believe that this new approach could be used to investigate the temporal and spatial aspects of any disease for which genealogical information is available.

    Research published in International Journal of Health Geographics, one of the first to assess the effects of time and space (when, where) across generations on increased risk of autism. Over time, the findings could lead to the identification of environmental factors, such as exposure to pollutants, that can have destructive effects on genetic information passed on from generation to generation, the researchers say.

    “Looking back at families and where and when they lived helped us detect clusters of individuals who might be at increased risk for autism among their offspring,” said U of U Health’s Department of Public Health. says James VanDerslice, an environmental epidemiologist at Senior author of the study. “Knowing that the parents and grandparents of children with autism shared space and time brings us closer to understanding the environmental factors that may have influenced this health condition.”

    Transgenerational epidemiological studies are difficult and time-consuming, says Rebecca Richards Steed, the study’s principal investigator and a graduate student in the Department of Geography at the University of Utah. In fact, most of these studies have been done in animals, which reproduce quickly and can be followed for several generations in a shorter period of time than humans.

    VanDerslice and Richards-Steed use existing technology in new ways to examine existing data available to parents and grandparents to identify locations and potential risk factors that increase disease risk in the next generation. By specifying the time period, we avoided this drawback.

    Researchers used the Utah Registry of Autism and Developmental Disabilities in conjunction with the Utah Population Database (UPDB) to identify parents and grandparents of children with autism born between 1989 and 2014. Did.

    UPDB’s birth certificates, driver’s license information, census and medical records helped scientists track when and where these individuals lived. UPDB is one of the few databases in the world that contains this kind of information.

    For comparison, we randomly selected parents and grandparents of children not diagnosed with autism from the UPDB database. The individual’s name was withheld from researchers.

    In all, VanDerslice and colleagues identified where 7,900 parents and 31,600 grandparents were born and raised. They identified 20 major clusters, or groups, scattered throughout the state. After analysis, 13 of the 20 clusters (9 grandparents, 4 parents) were associated with an increased risk of autism in their children or grandchildren. The odds of becoming autistic were about three times higher than expected.

    “What we’ve seen is consistent with current scientific understanding that paternal genetics is key to evolutionary change and adaptation,” says Richards Steed. In the case of , it is very likely that the signals, partly shaped by environmental experience, come from the paternal lineage passed on to the family.”

    Seven clusters, all located in rural areas, had a low risk of association between autism and family history.

    “We don’t quite understand why some rural areas appeared to have what we would call protective effects,” says Richards-Steed. It is certainly possible that he had

    “Based on our findings, we can say that what we are now exposed to is probably affecting not only us and our children, but possibly our children’s children as well. It means that there is

    Going forward, researchers will delve deeper into factors such as lifestyle that may help explain these results.

    “Evidence shows that our environment has a deterministic effect on our growth and development, including the germ cells we carry for our next generation,” he said. “Looking at the space and time that our ancestors shared can provide clues about environmental factors that may lead to biological changes that increase the risk of disease in future generations,” says VanDerslice. maybe.”

    Scientists believe that this new approach could be used to investigate the temporal and spatial aspects of other conditions for which genealogical information is available.

    “This idea is not unique to autism,” says Richards Steed. “This could be applied to any disease and could enhance our ability to understand how the confluence of genetic and environmental factors has long-term effects on family health.”

    For more information:
    Rebecca Richards, Steed et al., Evidence for transgenerational impact on autism spectrum disorders using multigenerational spatiotemporal cluster detection, International Journal of Health Geographics (2022). DOI: 10.1186/s12942-022-00313-4

    Courtesy of the University of Utah

    Quote: Autism Risk Related to When and Where Ancestors Lived (12 Jan 2023) from https://medicalxpress.com/news/2023-01-autism-forebears.html Jan 2023 Get on 12th

    This document is subject to copyright. No part may be reproduced without written permission, except in fair trade for personal research or research purposes. Content is provided for informational purposes only.





    Source link

    Share. Facebook Twitter Pinterest LinkedIn WhatsApp Reddit Tumblr Email
    adawebsitehelper_ts8fwm
    • Website

    Related Posts

    Autism January 27, 2023

    Jason Kelce and his wife, Kylie, are the driving force behind the Eagles Autism Foundation

    Autism January 27, 2023

    Steinhardt introduces bill to make traffic stops safer for autistic drivers

    Autism January 27, 2023

    NIH Program Study Links Prenatal Perfluorononanoic Acid Exposure to Pediatric Autism-Related Features

    Autism January 27, 2023

    NIH Program Study Links Prenatal Perfluorononanoic Acid Exposure to Pediatric Autism-Related Features

    Autism January 27, 2023

    ADHD strongly linked to anxiety, depression and autism: study

    Autism January 27, 2023

    Family remembers teen killed in Brooklyn apartment fire

    Leave A Reply Cancel Reply

    Don't Miss
    Society January 27, 2023

    Philly Mayor Richardson Dilworth Redevelopment Begins

    More than 20 years after John Turch purchased Mayor Richardson Dilworth’s former mansion in Washington…

    Brandt introduces bill to ban organ donation discrimination based on disability

    January 27, 2023

    Fusion of art, culture and literature

    January 27, 2023

    Retirement and Disability Research Consortium Cooperation Agreement – ​​InsuranceNewsNet

    January 27, 2023
    Stay In Touch
    • Facebook
    • Twitter
    • Pinterest
    • Instagram
    About Us

    This website provides information about disability and other things. Keep Supporting Us With the Latest News and we Will Provide the Best Of Our To Makes You Updated All Around The World News. Keep Sporting US.

    Our Picks

    Philly Mayor Richardson Dilworth Redevelopment Begins

    January 27, 2023

    Brandt introduces bill to ban organ donation discrimination based on disability

    January 27, 2023

    Fusion of art, culture and literature

    January 27, 2023

    Subscribe to Updates

    Get the latest creative news from SmartMag about art & design.

    Facebook Twitter Instagram Pinterest
    • Home
    • Contact us
    • DMCA
    • Privacy Policy
    © 2023 adawebsitehelper. Designed b yadawebsitehelper.

    Type above and press Enter to search. Press Esc to cancel.